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Department

Immunology
Local code : GAM

Preferred Sample Type

Immunoglobulin M (IgM)

Suitable Specimen Types

  • Serum
5-10 mL

Specimen Transport

.

Sample Processing in Laboratory

Usual

Sample Preparation

Centrifuge

Turnaround Time

3 days

Sample Stability

7 days when stored at 4C or frozen

Immunoglobulin M (IgM)

General Information

Quantitation of serum concentration of IgG,IgA and IgM is essential in the diagnosis and management of primary and secondary immunodeficiencies. It is also necessary for monitoring of patients receiving Immunoglubulin replacement therapy.

Charecteristic immunoglobulin changes have been descrbed in association with many other diseases and their determination may be helpful in differential diagnosis and disease monitoring.

Patient Preparation

None

Notes

None Given

Reference Range

Age related reference range:-

Cord 0.02-0.2g/L, 

0-2 weeks 0.05-0.2 g/L, 2-6 weeks 0.08-0.4 g/L, 6-12 weeks 0.15-0.7 g/L

3-6 months 0.2-1.0 g/L, 6-9 months 0.4-1.6 g/L,  9-12 months 0.6-2.1 g/L

1-2 yrs 0.5-2.2 g/L, 2-3 yrs 0.5-2.2 g/L, 3-6 yrs 0.5-2.0 g/L

6-9 yrs 0.5-1.8 g/L, 9-12 yrs 0.5-1.8 g/L 12-15 yrs 0.5-1.9 g/L

15-45 yrs 0.5-1.9 g/L   >45yrs 0.5-2.0 g/L  

Specifications

  • EQA Status:

    UK NEQAS for specific proteins