Preferred Sample Type
Suitable Specimen Types
- Serum
- Li Hep Plasma
Specimen Transport
Not applicable
Sample Processing in Laboratory
No special requirements
Sample Preparation
Centrifuge on arrival
Turnaround Time
1 daySample Stability
4oC
Alkaline Phosphatase (ALP)
General Information
ALP activity changes markedly throughout childhood and rises rapidly during the adolescent growth spurt, particularly in boys. Increases in bone ALP of 3.4-4.0 times the adult range can be seen during this time. Values of over 1000 U/L in teenage boys or 800 U/L in teenage girls require investigation.
Patient Preparation
None
Notes
No significant interference from haemolysis, icterus or lipaemia.
EDTA contamination decreases ALP activity.
Anticonvulsants, barbiturates, oral contraceptives can increase ALP activity.
Reference Range
Neonate (<4weeks) 70-380 U/L
4wks-16yrs 60-425 U/L
Adult 30-130 U/L
(Source : Pathology Harmony Recommendations)
Specifications
- EQA Scheme?: Yes
-
EQA Status:
UK NEQAS for Clinical Chemistry