TTGA
Preferred Sample Type
Suitable Specimen Types
- Serum
5-10 mL
Sample Processing in Laboratory
Usual
Sample Preparation
Usual
Turnaround Time
7 DaysSample Stability
Stored at 4oC
Tissue Transglutaminase Antibodies (TTG)
General Information
Some indications: Coeliac Disease, Dermatitis, Herpetiformis
Please note Lithium Heparin samples are unsuitable for the measurement of Tissue Transglutaminase antibodies ( IgA and IgG)
Patient Preparation
None
Notes
Patients with known or suspected IgA deficiency will have TTg IgG antibodies tested. In addition patients with suspected IgA deficiency will also have Immunoglobulins IgA, IgG and IgM levels measured in line with NICE guidelines
All positive TTG results are confirmed by Endomysial antibody assay.
Reference Range
Negative = <7 U/mL
Weak positive = 7-10 U/mL
Positive = >10 U/mL
Normal result = Negative
Specifications
- EQA Scheme?: Yes
-
EQA Status:
UK NEQAS eqa scheme for Coeliac serology.