Preferred Sample Type
Suitable Specimen Types
- Serum
- EDTA Plasma
- Li Hep Plasma
Specimen Transport
First class postSample Processing in Laboratory
Place sample in toxicology rack.Sample Preparation
None requiredTurnaround Time
3 days.Sample Stability
Keep refrigerated. 4 degrees.Oxycodone
General Information
Oxycodone is a semisynthetic narcotic analgesic used since 1939 for relief of moderate to severe pain. Given subcutaneously, the drug is approximately equipotent with morphine, but it has a higher oral/parenteral efficacy ratio. The usual adult dose is 2.5 - 5 mg every 4 - 6 hours for the normal release forms and 10 - 80 mg every 12 hours for the extended release forms.
The adverse effects of oxycodone therapy include nausea, somnolence, dizziness, asthenia, diaphoresis, constipation and urinary retention. Oxycodone in overdosage is capable of producing stupor, coma, muscle flaccidity, severe respiratory depression, depression, hypotension and cardiac arrest. Naloxone is a specific antidote.
Patient Preparation
No patient preperation required.
Notes
Oxycodone measured by LC-MS/MS
Reference Range
Units ug/L
Please contact the laboratory for guidance in therapy
Please contact the laboratory if oxycodone measurement is required for therapeutic monitoring purposes.
Specifications
- EQA Scheme?: Yes
- EQA Status: LGC QUARTZ, LGC CLIN TOX