MOG
Preferred Sample Type
Suitable Specimen Types
- EDTA Plasma
1 mL
Specimen Transport
1st class post overnight to referral laboratorySample Processing in Laboratory
Centrifuge, Seperate then store serum at 4C prior to transport to referral LaboratoryTurnaround Time
14 days from receipt at referral laboratory.Sample Stability
Sample stable at 4C prior to transport to referral laboratoryMyelin Oligodendrocyte Glycoprotein MOG
General Information
Myelin oligodendrocyte glycoprotein (MOG) is a dominant target for demyelinating autoantibodies in multiple sclerosis (MS). Antibody-mediated demyelination is complement and/or antibody-dependent cell-mediated cytotoxicity (ADCC) dependent. Pathogenic MOG-specific antibodies recognize cell surface and largely conformation-dependent epitopes. The prevalence of anti-MOG antibodies in pediatric MS/acute disseminated encephalomyelitis (ADEM) patients suggests these contribute to demyelination in these diseases.Reference Range
NASpecifications
- EQA Scheme?: No
- EQA Status: No EQA scheme available.