MUSK
Preferred Sample Type
Suitable Specimen Types
- Serum
1 mL
Specimen Transport
1st class post overnight to referral laboratorySample Processing in Laboratory
Centrifuge, Seperate then store serum at 4C prior to transport to referral LaboratoryTurnaround Time
21 days from receipt at referral laboratory.Sample Stability
Stable at 4CMuscle Specific Tyrosine Kinase (MUSK)
General Information
Muscle specific tyrosine kinase (MUSK) is a surface membrane enzyme that is essential in aggregating Acetylcholine receptor during the development of the neuromuscular junction. Recent studies have shown that antibodies to Musk are present in 40% to 50% of patients with generalized Acetylcholine Receptor seronegative MG. Anti-Musk antibodies have not been found in patients with purely ocular myasthenia or in those with anti-acetylcholine receptor antibodies.
Reference Range
Qualitative test. Normal result would be negative
Specifications
- EQA Scheme?: No
- EQA Status: No EQA scheme currently available.