Preferred Sample Type
Suitable Specimen Types
- Serum
- EDTA Plasma
- Li Hep Plasma
Specimen Transport
First class postSample Processing in Laboratory
Place sample in toxicology rack.Sample Preparation
None requiredTurnaround Time
3 days.Sample Stability
Keep refrigerated. 4 degrees.Midazolam
General Information
Midazolam is an imidazobenzodiazepine derivative used as a preoperative medication, sedative-hypnotic and anaesthetic induction agent.
Adverse effects of midazolam include respiratory depression, apnea and hypotension; anterograde amnesia may last as long as 2 hours after injection
Please note, this assay is for the quantitative determination of midazolam in blood. Benzodiazepines (diazepam, nordiazepam, temazepam, oxazepam, flunitrazepam, lorazepam, midazolam & nitrazepam) use may also be detected via our urinary Drugs of Abuse Screen by LC-MS/MS.
Patient Preparation
No patient preperation required.
Notes
Midazolam measured by LC-MS/MS
Reference Range
Toxicity associated with midazolam levels > 1.0 mg/L. (Schulz et al. Critical Care 2012, 16:R136).
Please contact the laboratory if midazolam measurement is required for therapeutic monitoring purposes.
Specifications
- EQA Scheme?: Yes
- EQA Status: LGC QUARTZ, LGC CLIN TOX