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Department

Toxicology

Preferred Sample Type

Melphalan (Alkeran)

Suitable Specimen Types

  • Serum
  • EDTA Plasma
  • Li Hep Plasma
500 ul of serum/plasma

Specimen Transport

Usual

Sample Processing in Laboratory

Centrifuge and place in toxicology box in cold room.

Sample Preparation

Centrifuge

Turnaround Time

5 working days

Sample Stability

4 ºC

Melphalan (Alkeran)

General Information

Melphalan (phenylalanine nitrogen mustard, melfalan, L-PAM, L-sarcolysine, Alkeran, Sarcoclorin) is a synthetic alkylating agent that has been used clinically since 1970 as an antineoplastic agent. It is used to treat myeloma, melanoma and ovarian cancer.

The adverse effects resulting from melphalan therapy include nausea, vomiting, diahorrea, bone marrow suppresion, alopecia, haemolytic anaemia and hepatotoxicity. 

Patient Preparation

None required.

Notes

Please avoid use of gel seperator tubes

Reference Range

No reference range available. 

Specifications

  • EQA Scheme?: No