Preferred Sample Type
Suitable Specimen Types
- Serum
- EDTA Plasma
- Li Hep Plasma
Sample Processing in Laboratory
NULL
Sample Preparation
Centrifuge and separate serum
Turnaround Time
7 daysSample Stability
store frozen at -20oC
Mast Cell Tryptase
General Information
Isolated tryptase concentrations may be of some value in the assesment of allergic disorders resulting in anaphylaxis, and Mast cell syndromes.
Investigation of anaphylactic reactions would be better conducted with serial samples collected within one hour of reaction and subsequently at 3 and 24 hours post reaction.
Inherent elevations of plasma tryptase are reported as increasing the risk of severe allergic or anaphylactic reactions to hymenoptera stings.
Patient Preparation
Post suspected anaphylactic reaction
Notes
Take serial samples in the first hour, 3 hours post and 24 hours after onset of anaphylaxis. Clearly label the sample and request form with date and time to establish the time-line
Reference Range
2-14 ug/L
Source of Reference Range
Protein Reference Unit handbook of Clinical Immunochemistry 8th editionSpecifications
- EQA Scheme?: Yes
-
EQA Status:
EQA scheme run by UKNEQAS