Suitable Specimen Types
- Serum
- EDTA Plasma
- Li Hep Plasma
Specimen Transport
First class postSample Processing in Laboratory
Place sample in toxicology rack.Sample Preparation
None requiredTurnaround Time
3 days.Sample Stability
Keep refrigerated. 4 degrees.Ketamine
General Information
Ketamine is a weakly basic amino compound which is used as an anesthetic induction agent. It is structurally and pharmacologically related to phenylcyclidine (PCP), a drug which failed clinical trials due to its unpleasant side effects during anaesthetic recovery but became a popular street drug. Ketamine has also received attention as a drug of abuse.
Adverse reactions to ketamine include hallucinations, delerium, irrational behavior, blurred vision, nausea, vomiting, respiratory stimulation or depression, tachycardia or bradycardia, hypertension or hypotension, seizures and cardiac arrhythmia.
Please note, this assay is for the quantitative determination of ketamine in blood. Ketamine use may also be detected via our urinary Drugs of Abuse Screen by LC-MS/MS.
Patient Preparation
No patient preperation required.
Notes
Ketamine is measured by HPLC-DAD.
Please note this assay is not currently UKAS accredited
Reference Range
Therapeutic use of ketamine (i.v) for sedation is effective at average concentrations >0.6 mg/L. (Clarke's Analysis of Drugs & Poisons, Third Edition)
Specifications
- EQA Scheme?: Yes
- EQA Status: LGC QUARTZ, LGC CLIN TOX