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Local code : HIST

Preferred Sample Type

Histone Antibodies

Suitable Specimen Types

  • Serum
2ml serum

Specimen Transport

1st class post overnight to referral laboratory

Sample Processing in Laboratory

Sample separated and sent to referral laboratory

Turnaround Time

10 days

Sample Stability

Sample stable at 4C prior to transport to referral laboratory

Histone Antibodies

General Information

Anti-histone antibodies are found in patients with SLE and patients with DIL. In SLE, anti-histone antibodies do not provide any better diagnostic information than DNA and anti-nuclear antibodies but in drug induced lupus, a typical antibody profile consists of anti-nuclear antibodies, anti-histone antibodies but rarely dsDNA antibodies and extractable nuclear antibodies

Reference Range

Normal result = <40 U/mL. .

Source of Reference Range

Reference range established by kit manufacturer and verified in-house by referral laboratory

Specifications

  • EQA Scheme?: No
  • EQA Status: No EQA scheme currently available.