Local code : ANA
Preferred Sample Type
Suitable Specimen Types
- Serum
5-10 mL
Sample Processing in Laboratory
Usual
Sample Preparation
Usual
Turnaround Time
Up to 5 daysSample Stability
Stored at 4oC
Centromere Antibody
General Information
Centromere antibodies are seen in systemic sclerosis in its limited cutaneous form and in the CREST variant.
In patients with Raynaud's phenomenon the presence of centromere antibody signifies an increased chance of developing a rheumatic disease.
Can occur in up to 20% of patients with PBC
Presence of these antibodies is reported in the anti nuclear antibody screen assay.
Reference Range
Negative
Specifications
- EQA Scheme?: Yes
-
EQA Status:
NEQAS eqa scheme for nuclear and related antigens