AESS
Preferred Sample Type
Suitable Specimen Types
- Serum
- CSF
1 mL If CSF sample minimum volume of 250 uL
Specimen Transport
Overnight to reference laboratorySample Processing in Laboratory
Samples should be centrifuged and stored at 4CTurnaround Time
14 days from receipt at referral laboratory.Sample Stability
Stable at 4CAuto-immune encephalitis syndrome screen
General Information
Approximately 50% of encepahlitis with unknown cause, Some of these cases (with and without associated tumors) have been identified as having antibodies directed against neuronal cell surface molecules. This causes disruption of neuronal transmission leading to abnormal CNS function. The Autoimmune encephalitis screen – transfected cell based assay consists of NMDAR: Anti-N-methyl-D-aspartate receptor AMPA1, AMPA2, Alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic type 1 & 2 LGI1 Leucine-rich glioma inactivated protein 1 CASPR2 Contactin-associated protein 2 GABA receptor B1 GABABR1 Gamma-aminobutyric acid receptor type B1 .Reference Range
NegativeSource of Reference Range
Supplied by referral laboratorySpecifications
- EQA Scheme?: No
- EQA Status: No EQA scheme currently available.