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Department

Referred Work
AQP4

Preferred Sample Type

Aquaporin 4 antibodies (AQP4)

Suitable Specimen Types

  • Serum
4 mL

Specimen Transport

1st class post overnight to referral laboratory

Sample Stability

Stored at 4C

Aquaporin 4 antibodies (AQP4)

General Information

Antibodies directed against the Central nervous system water channel protein Aquaporin 4 (AQP4) have been found in the demyelinating disease Neuromyelitis Optica (NMO) as well as its spectrum disorders (NMOSD), which affect in particular the optical nerve and spinal cord. Detection of AQP4 antibodies allows discrimination from multiple sclerosis its most important differential diagnosis.

Patient Preparation

No special preparation required

Reference Range

Normal result is negative

Source of Reference Range

Provided by reference laboratory

Specifications

  • EQA Scheme?: No
  • EQA Status: No EQA scheme currently available.