Preferred Sample Type
Suitable Specimen Types
- Serum
Sample Processing in Laboratory
Usual
Sample Preparation
usual
Turnaround Time
7Sample Stability
stored at 4oC
anti Cardiolipin antibody + Anti Beta 2 glycoprotein
General Information
Some clinical indications:- one or more clinical episodes of arterial, venous or small vessel thrombosis.
One or more unexplained deaths of morphologically normal fetus at or beyond the 10th week of pregnancy.
Notes
Both Anti Cardiolipin and Beta 2 Glycoprotein 1 are useful in the assesment of risk of thrombosis in patients with SLE or related disorders, for monitoring of patients at risk for foetal loss.
Reference Range
Consider IgG Anti cardiolipin antibody abnormal only if >23.8 U/mL
IgM Anti cardiolipin antibody abnormal only if >29.9 U/mL
(99th centile of normal), present on two or more occasions,
at least 12 weeks apart.
Consider IgG B2GP1 abnormal only if >17.7 U/ml
IgM B2GP1 abnormal only if >5.7 U/mL
(99th centile of normal), present on two or more occasions,
at least 12 weeks apart.
Specifications
- EQA Scheme?: Yes
-
EQA Status:
UK NEQAS scheme for Phospholipid antibodies