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Department

Biochemistry

Preferred Sample Type

Taurine

Suitable Specimen Types

  • Serum
5 mL

Specimen Transport

First class post.

Samples are sent to the Security Office in the foyer of the Medical School Vincent Drive - labelled for attention of Dr Davies Pharmacology

Sample Processing in Laboratory

Usual

Sample Preparation

Centrifuge sample and separate serum

Turnaround Time

Variable

Sample Stability

4 ºC

Taurine

General Information

Taurine or 2-aminoethanesulfonic acid is an organic acid. It has several physiological functions, e.g. in bile acid formation, as an osmolyte by cell volume regulation, in the heart, in the retina, in the formation of N-chlorotaurine by reaction with hypochlorous acid in leucocytes, and possibly for intracellular scavenging of carbonyl groups. Several links can be established between altered taurine metabolism and the development of cellular dysfunctions in diabetes which cause the clinical complications observed in diabetes, e.g. retinopathy, neuropathy, nephropathy, cardiomyopathy, platelet aggregation, endothelial dysfunction and atherosclerosis.

Patient Preparation

None

Notes

Glycated Haemoglobin (HbA1c) is also requested on an EDTA sample (done at BHH).

Reference Range

Povided by reference laboratory

Specifications

  • EQA Scheme?: No