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Preferred Sample Type

CTX bone marker (Collagen Type I cross-linked C telopeptide; bone markers)

Suitable Specimen Types

  • EDTA Plasma
0.5mL minimum plasma

Sample Processing in Laboratory

Separate and freeze plasma within 24 hours of specimen collection. Transport to referral laboratory on dry ice.

Sample Preparation

Spin and freeze plasma

Sample Stability

CTX is relatively stable in EDTA containers - plasma should be separated and frozen within 24 hours of specimen collection.

CTX bone marker (Collagen Type I cross-linked C telopeptide; bone markers)

Patient Preparation

Suggest take samples for monitoring at approximately the same time of day to improve interpretation of results. Fasting is not required for this test.

Reference Range

 

Plasma CTX (ug/L)

 

Male

Female

< 1 month

0.44 – 2.27

1 month – 1 year

0.20 – 2.31

1 -9 years

0.15 – 0.82

Age/gender specific ranges

9-14 yrs: 0.23 – 1.24

9-11 yrs: 0.30 – 0.10

 

14-17 yrs: 0.24 – 1.73

11-13 yrs: 0.33 – 1.70

 

17-19yrs: 0.10 – 0.79

13-15yrs: 0.14 - 1.20

 

 

15-19 yrs: 0.05 – 0.58

Adults

0.1 – 0.5 (males/pre-menopausal females)

 
Source: referral laboratory (July 2014)