Preferred Sample Type
Suitable Specimen Types
- Serum
Specimen Transport
Not applicable
Sample Processing in Laboratory
Usual
Sample Preparation
Centrifuge. Lithium heparin or EDTA plasma may be used.
Turnaround Time
1 daySample Stability
Store at 4ºC prior to assay.
Samples stored post analysis in Immunology SFS filing system.
Stability: 3 days at 2- 8°C, 6 months at -20°C
Beta-2-Microglobulin (B2M)
General Information
The serum concentration of B2M is inversely related to the GFR, and a raised value is an early indicator or renal tubular damage. It is however, also increased in inflammatory conditions, haematological and lymphoid malignancies and a variety of non-malignant conditions e.g. AIDS.
Patient Preparation
None
Notes
To help evaluate the severity and prognosis of multiple myeloma, leukemia, or lymphoma; to distinguish between kidney disorders and to detect kidney damage
Reference Range
Foetal serum 2.3 - 4.7 mg/L
Serum (Adult) 1.2 – 2.4 mg/L
Source PRU Handbook of Clinical Immunochem
Specifications
- EQA Scheme?: Yes
-
EQA Status:
NEQAS