Preferred Sample Type
Suitable Specimen Types
- Serum
Sample Processing in Laboratory
Centrifuge and process ASAPSample Preparation
If unable to send immeadiately please refrigerate sampleTurnaround Time
2 daysSample Stability
Up to 7 days if stored at 2 to 8°CAmikacin Antibiotic Assay
General Information
Amikacin is a semi-synthetic antibiotic that exhibits bactericidal activity against a wide range of pathogens. The determination of serum drug levels is required to achieve optimum therapeutic efficacy and minimize toxicity.
Patient Preparation
For pre-dose levels take the sample 15 minutes before dose.
For post dose levels take the sample 1 hour after the dose is given.
Notes
From Monday 3rd 2018, amikacin requests will be processed at the Heartlands laboratory site.
Amikacin is not currently UKAS accredited. This will be assessed in October 2018.
Reference Range
For once daily dosing aim for pre-dose levels (taken 15 minutes before dose) of <5mg/L and post dose levels (taken 1 hour post dose) of >35mg/L.
For multiple daily dosing aim for pre-dose levels of <10mg/L and post dose levels of 20-30mg/L.
Source of Reference Range
Guidelines from Bristol Reference laboratorySpecifications
- EQA Scheme?: Yes
- EQA Status: UK NEQAS for Antibiotics