Latest News

  • Change to Feto-Maternal Haemorrhage (FMH) Anti-D Calculation

    Change to Feto-Maternal Haemorrhage (FMH) Anti-D Calculation

    Item Author Mark Hill

    From 25/04/16 we have adjusted the way Anti-D is calculated in our FMH screen by flow cytometry. The bleed is still reported in millilitres as previously however the suggested dose of Anti-D required to cover the bleed also takes into account the uncertainty of measurement of this technique in our laboratory. This may result in a slightly higher dose than expected but will ensure that bleeds are appropriately covered, especially those requiring multiple injections. For further information click here or contact the laboratory on 0121 42(40704)

  • Apixaban & Rivaroxaban

    Apixaban & Rivaroxaban

    Item Author Mark Hill

    Haematology are now offering assays to measure the new oral anticoagulant drugs Apixaban and Rivaroxaban. Both drugs are direct factor Xa inhibitors. Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes mellitus, or symptomatic heart failure. Apixaban and other newer anticoagulants (dabigatran and rivaroxaban) appear equally effective as warfarin in preventing non-hemorrhagic stroke in people with atrial fibrillation and are associated with lower risk of intracranial bleeding. For further information please contact the laboratory on 0121 424 0908 (internal ext 40908) or for clinical advice please contact the On Call Haematologist via switchboard.
  • 24/7 Provision of Ethylene Glycol Measurement at Heartlands Hospital

    24/7 Provision of Ethylene Glycol Measurement at Heartlands Hospital

    Item Author Alex Lawson

    From the 9th of February 2016, ethlene glycol measurement is available 24 hours a day, 7 days a week at Birmingham Heartlands Hospital.

    Ethylene glycol is an odourless and highly toxic compound found in various household products. Cases of ethylene glycol poisoning are rare but often fatal unless treated promptly. Early recognition is thus critical for treatment and recovery of patients. Patients with ethylene glycol poisoning typically present in the acute setting with a high anion gap metabolic acidosis, altered mental status and acute kidney injury. Indirect testing of ethylene glycol ingestion (e.g. lactate, osmolar gap & anion gap), although potentially helpful, are not accurate estimators of the presence of ethylene glycol. Urgent, accurate measurement of ethylene glycol should be sought if ingestion is suspected. Measurement of ethylene glycol
    has not always been readily available due to specialised methodologies required; and often comes at a prohibitively high price for access to these assays out of normal working hours.

    We have therefore implemented a rapid, automated, cost effective assay for the measurement of ethylene glycol which is readily available 24/7.
    GC-MS measurement of ethylene glycol and diethylene glycol is still available on specific request. 

    Additional Information:
    Please contact the laboratory (41185 / 0121 424 1185) and ask to speak to a biomedical scientist or biochemist before sending a specimen.

    If you wish to discuss a particular patient please bleep the duty biochemist / toxicologist on 2506 or 3289 in work hours, or the on-call consultant via switchboard (0121 424 2000).

    For external users, please send samples urgently via courier to: Pathology Reception, Birmingham Heartlands Hospital, Bordesley Green East, B9 5SS. Couriers should use the Yardley Green Road Entrance to the hospital. At night, vehicular access is limited but access on foot is available via the pedestrian gate.

  • PTH Update (From 21st December 2015)

    PTH Update (From 21st December 2015)

    Item Author Craig Webster

    From Monday 21th Decemeber we will no longer be provide dual reporting of PTH results. HEFT will provide PTH measurements using the Abbott Architect assay only. Please take note of the new method specific reference range for PTH.

    Reference Interval (Abbott): 1.6 – 7.2 pmol/L

     

    Note: There will be no change to specimen handling instructions. EDTA plasma is still the recommended sample type.

    If you have any queries or comments please contact Craig Webster (Clinical Lead for Blood Sciences) by email or the Duty Biochemist on Bleep 2506.

    Note re accreditation status. This PTH assay is currently not on our UKAS accreditation scope.

    Tests not appearing on this scope are either under consideration or in the process of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff. 

Introduction

Written by Craig Webster on .

This handbook encompasses all disciplines of Laboratory Medicine at Birmingham Heartlands, Solihull and Good Hope Hospitals. It has been designed to provide the busy general practitioner and hospital doctor more readily available information regarding our services. 

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You can search or browse our test directory here. This database includes details on all our tests and recommended profiles for the investigation of common presenting complaints.
 

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Apixaban and Rivaroxaban Assays

Written by Mark Hill on .

Haematology are now offering assays to measure the new oral anticoagulant drugs Apixaban and Rivaroxaban. Both drugs are direct factor Xa inhibitors. Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes mellitus, or symptomatic heart failure. Apixaban and other newer anticoagulants (dabigatran and rivaroxaban) appear equally effective as warfarin in preventing non-hemorrhagic stroke in people with atrial fibrillation and are associated with lower risk of intracranial bleeding. For further information please contact the laboratory on 0121 424 0908 (internal ext 40908) or for clinical advice please contact the On Call Haematologist via switchboard.