Preferred Sample Type

Dilute Russells Viper Venom Test - DRVV (Lupus Screen)
2x 2.7mL

Specimen Transport

Standard transport to laboratory

Sample Processing in Laboratory

Sample should be centrifuged

Sample Preparation

To arrive in laboratory within 4 hours of collection. Samples for any coagulation tests must be filled to within a tolerance of 10% of the fill line indicated on the sample tube. Any sample filled above or below this level will be reported as overfilled o

Turnaround Time

10 days

Sample Stability

8 hours

Dilute Russells Viper Venom Test - DRVV (Lupus Screen)


For the effects of direct oral anticoagulants on coagulation tests click here

DOAC Stop can be applied to the sample to remove all interference from direct oral anticoagulants. If you are requesting a thrombophilia or lupus anticoagulant screen and your patient is on a DOAC, please state clearly on the request form together with which anticoagulant.

Reference Range

Ratio 0.9-1.1

LC ratio > 2.0         Strong lupus anticoagulant detected
LC ratio 1.5 – 2.0  Moderate lupus anticoagulant detected
LC ratio 1.2 – 1.5  Weak lupus anticoagulant detected


  • EQA Scheme?: Yes
  • EQA Status: NEQAS

The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link:

  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217
  • United Kingdom Health Security Agency laboratory is a UKAS accredited medical laboratory No.8213

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database:

Protection of personal information - Laboratory Medicine comply with the Trust Data Protection policy and have procedures in place to allow the Directorate and its employees to comply with the Data Protection act  1998 and associated best practice and guidance.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235