Preferred Sample Type

Alanine Aminotransferase (ALT)

Suitable Specimen Types

  • Serum
  • Li Hep Plasma
0.2 mL blood (Paediatric minimum volume is 30 uL)

Specimen Transport

Not applicable

Sample Processing in Laboratory

No special requirements

Sample Preparation

Centrifuge on arrival

Turnaround Time

1 day

Sample Stability

4 ÂșC

Alanine Aminotransferase (ALT)

General Information

Alanine aminotransferase (glutamate pyruvate transaminase) belongs to the transaminases, which catalyse the interconversion of amino acids and a-ketoacids by transfer of amino groups.

Elevated levels of the transaminases can indicate myocardial infarction, hepatic disease, muscular dystrophy and organ damage.  However, serum elevations of ALT activities are rarely observed except in parenchymal liver disease, since ALT is a more liver-specific enzyme than AST.

Patient Preparation



None Given

Reference Range

0-55 IU/L

Source of Reference Range

Abbott Diagnostics


  • EQA Scheme?: Yes
  • EQA Status:

    UK NEQAS for Clinical Chemistry Scheme

The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link:

  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217
  • United Kingdom Health Security Agency laboratory is a UKAS accredited medical laboratory No.8213

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database:

Protection of personal information - Laboratory Medicine comply with the Trust Data Protection policy and have procedures in place to allow the Directorate and its employees to comply with the Data Protection act  1998 and associated best practice and guidance.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235