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Research Investigations / Clinical Trials (Biochemistry)

Before undertaking any biochemical investigations which are to be conducted as part of a research project or clinical trial, the protocol and workload entailed must be discussed with the Department. Failure to do so may jeopardise the project at a later stage with unfortunate consequences.

Current Projects

ITU and Statins

Prof Fang Gow, Alan Jones

Oxidative Stress and the Development of Asthma

C Webster
 
Includes Isoprostene Assay Development, C Webster in conjunction with Respiratory Medicine and Immunology.
The department has developed an assay for 8-Isoprostane measured by tandem mass spectroscopy

Platelet Activating Factor assays and Anaphylaxis

This project won the Gaddie Poster Prize. We have developed assays for PAF and PAF activity.

Vitamin D in Diabetes

The department has a number of extensive research projects in Vitamin D. We have developed and have been running highly specific tandem mass spectroscopy for vitamin D and some of the metabolites of vitamin D for over 3 years. We have had a number of posters and publications in this area.

Vitamin D Assay Standardisation

Collaborative Project amongst MSMS Users Nationally, J Heynes

Diabetes in Community Audits

Generate database of hospital GTT tests and compare with community database Telepath trawl and merge with HISS data 

Dr Mailk, J Heynes, K Gordon, C Webster, Alan Jones

UV and MS

Sud Rammachandran

Case Reports

Sud Rammachandran and Various

BNP Analysis

Sud Ramachandran, T Pryor

Future Projects

Vitamin D Research Program

Comprehensive and expandable program of research into vitamin D metabolism and effect.

C Webster

We have also supervised a large number or MSc projects (Birmingham Univeristy, Wolverhampton University) and have been highly successful in gaining passes and credits. Projects in the pas have included:

  • Mevolnate Analysis
  • Vitamins A and E by Tandem Mass Spectroscopy

Please visit the directorates R&D section for more information on the services and support we can offer for research projects and clinical trails

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Tests not appearing on this scope are either under consideration or in the process of accreditation and so currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

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