HEFT Directorate of Pathology Blog

Welcome to the Directorate of Laboratory Medicine blog. Here you will find all the latest news and informaiton relevant to the directorate and its services.

 

 

30
June
2014

TB Genomics Service Pilot Project

TB Genomics Service: Pilot project to start next month

PHE Birmingham are launching our TB Genomics Service pilot project next month.

Background

  • In the last 10-months we have participated in an eight-centre international collaboration study on TB Whole Genome Sequencing (WGS) led by Oxford which has used DNA extracted from MGIT. 
  • The Oxford led project is a feasibility study on the use of WGS in TB diagnosis, resistance profiling and epidemiological mapping of outbreaks. During this Feasibility study, working with our colleagues at Oxford, DNA extraction and MiSeq sequencing methodologies have been established at Heartlands. Raw sequence data has been shared with Oxford through a cloud setup and analysis reports (on mycobacterial species identity, drug resistance predictions and strain typing) received within 48 hours of the raw data being uploaded.

Categories: Microbiology

18
June
2014

Withdrawal of IL28B test

Public Health England  Public Health Laboratory Birmingham will no longer be offering an IL28B testing service. Please see Letter to Users for further details.

Categories: Microbiology

29
May
2014

Change to Thyroid requesting

Change to Thyroid requesting

As of 27th May 2014 TSH only will be the frontline test for investigating Thyroid function. If the TSH is <0.35 mU/L or >4.9 mU/L a fT4 will be automatically added on to the request. If the TSH is <0.1 mU/L fT3 will also be added. The reason for this is to encourage more appropriate use of the thyroid tests. If you have any queries or concerns please contact the duty biochemist (bleep 2506).

Written by: Craig Webster Categories: Blood Sciences, Biochemistry

04
March
2014

PTH Update

PTH Update

From 27th February 2014 we will be resuming a PTH service from Heartlands using the Roche intact PTH assay (iPTH).  It is difficult to directly compare results determined from the previous Abbott assay to the Roche assay as the Abbott method had a significant positive bias with respect to Roche, therefore you should expect slightly lower results now.  The reference range for iPTH on the Roche assay is 1.6-6.9 pmol/L. 

 

Analysis will be batched daily, Monday-Friday.  As previously plasma from EDTA samples is the preferred sample type.  If there is a need for an urgent PTH the current process of contacting the duty biochemist/duty consultant will continue and the urgent pathway implemented. If there are any queries clinicians should contact the duty biochemist/duty consultant.

Written by: Craig Webster Categories: Blood Sciences, Biochemistry

08
January
2014

NEW THIN URINE TUBES FOR MC&S

NEW THIN URINE TUBES FOR MC&S

The PHE Public Health Laboratory Birmingham are changing the type of sample tubes required for urines sent for microscopy, culture and sensitivity testing (M,C&S). The new tubes will fit directly onto the laboratory’s new automated analysers which will speed up the processing of urines. This is part of the quality improvement and technical modernisation strategy of the laboratory. The smaller volume required to fill the new style boric acid containers should also reduce the number of samples we cannot process due to them being under-filled. For urines for tests other than M,C&S (e.g. Pregnancy test, legionella antigen, virology, TB culture, chlamydia and gonorrhoea) please continue to use the sample containers currently required for those tests. For CSF's and any sterile sites e.g. Ascitic Fluid, Knee Aspirates, Pleural Fluids, PD Fluids, Pus samples and any other fluid samples please send them in a 20ml universal. Urines for MC&S in a 20ml universal will be rejected, so please send in correct container. Please check your requisition form to make sure you can order both types of specimwn containers.

Categories: Microbiology, General

20
September
2013

Urines for M,C&S – Change of Sample Tubes

The PHE Public Health Laboratory Birmingham (at Heartlands Hospital) are changing the type of sample tubes required for urines sent for microscopy, culture and sensitivity testing (M,C&S)

Urines for M,C&S – Change of Sample Tubes

What are the new urine sample tubes like?

  • The new tubes are smaller and have a 10ml capacity.
  • They will still be available in both a “red top” boric acid containing version and plain “white top” version.

Written by: Craig Webster Categories: Microbiology, General

10
June
2013

From Saturday May 25th the Weekend Phlebotomy service at Boots has transferred back to Solihull Hospital

From Saturday May 25th the Weekend Phlebotomy service at Boots has transferred back to Solihull Hospital

From Saturday May 25th the Phlebotomy service at Boots has transferred back to Solihull Hospital into the new expanded facility. Access is via the South entrance and is signposted.

  • Saturday 8.30 – 12.00
  • Sunday 10.30 – 13.30

Written by: Craig Webster Categories: General

20
March
2013

Prolactin Assay Change

The prolactin assay will be changing in the next few weeks. This is because it has been re-standardised by the manufacturer.

The new assay gives results approximately 25% lower than what is currently reported. 

Categories: Biochemistry, General

30
June
2014

PHE Birmingham Newsletter: Summer 2014

Please find the Summer 2014 edition of the PHE Birmingham Newsletter here

Categories: Microbiology

10
June
2014

Notification of changes to CA19-9

On Wednesday 11th June the method for the CA19-9 assay at HEFT will change from the Siemens Immulite assay to the Roche assay. Our comparisons have shown that the results are comparable in most cases; however, there were some samples which did show a poor correlation.  We are therefore going to dual report results for a period to allow transition of serially monitored patients to the new CA199 assay.

Further more detailed information is available on request. If you have any queries or comments please contact Craig Webster (Clinical Lead for Blood Sciences) by email or ext 42930.

Written by: Craig Webster Categories: Blood Sciences, Biochemistry

29
May
2014

Laboratory Information System Migration

Laboratory Information System Migration
In order to bring systems in line with the restructured laboratory services the Laboratory Medicine directorate will be migrating to new Laboratory Information System Databases for Blood Sciences and Microbiology.
 
The migration is due to commence at 8am Monday 2nd June.
 
No downtime is anticipated but there may be some temporary disruption as the migration progresses.
 
The Blood Sciences System will replace what is currently the separate disciplines of Chemistry, Haematology and Immunology as a single department. As such the ICE Reporting System will display reports as Blood Sciences (Orange highlighting).

Categories: Blood Sciences, Microbiology, Cellular Pathology, Haematology, Immunology, Biochemistry, General

14
February
2014

Important Notice re PTH analysis

Abbott Diagnostics withdraws PTH assay with Immediate Effect

Important Notice re PTH analysis
Dear Colleague,

Product Recall: Parathyroid hormone (PTH) test

Abbott Laboratories who supply our major laboratory biochemistry analysers and the reagents for the majority of the tests we run on these machines, have issued a global product recall for their parathyroid hormone (PTH) test. We received an initial warning of this recall by phone on 13th February and written confirmation and further details this morning. We have been instructed to stop using their PTH assay immediately and destroy our current stocks of reagent.

Written by: Craig Webster Categories: Blood Sciences, Biochemistry

29
October
2013

New telephone number for Microbiology

New telephone number for Microbiology

7th November Microbiology will be changing their telephone number to 0121 424 3111 please? This is an automated system and users should follow the instructions given.

Written by: Craig Webster Categories: Microbiology, General

30
July
2013

New Testosterone Assay - For use in males

New Testosterone Assay - For use in males

The testosterone assay for male patients will be changing the week starting 5th August 2013. This is due to a re-formulation of the reagent by the manufacturer. There will be a change in the reference post-change:

4.9 – 32.0 nmol/L

A comment will be appended to all reports for a short period of time once the assay change has occurred.

Categories: Biochemistry

02
April
2013

Persistently Elevated LFTs and What to Do

Persistently Elevated LFTs and What to Do

A podcast on the interpretation of LFTs

Written by: Craig Webster Categories: Biochemistry

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