Clinical Advice


Faecal Calprotectin and Local IBS Guidelines

Faecal Calprotectin (FCAL) is a protein that is released into the intestines in excess when there is any inflammation. Many people with irritable bowel syndrome (IBS) have unnecessary invasive hospital investigations before their condition is diagnosed. Use of FCAL testing may lead to a reduction in the number of investigations being requested for people with a high likelihood of an IBS diagnosis. This will:

• Improve the patient experience for those with IBS and reduce the number of patients undergoing invasive procedures within secondary care.

• Reduce outpatient referrals into secondary care.

• Increase the numbers accessing rapid diagnosis for IBS/IBD.

• Improve pathways for the management of IBS.

• Provide a structured programme to aid decision making in primary care.


Categories: Clinical Advice, Blood Sciences, Biochemistry


PTH Update (From 21st December 2015)

From Monday 21th Decemeber we will no longer be provide dual reporting of PTH results. HEFT will provide PTH measurements using the Abbott Architect assay only. Please take note of the new method specific reference range for PTH.

Reference Interval (Abbott): 1.6 – 7.2 pmol/L


Note: There will be no change to specimen handling instructions. EDTA plasma is still the recommended sample type.

If you have any queries or comments please contact Craig Webster (Clinical Lead for Blood Sciences) by email or the Duty Biochemist on Bleep 2506.

Note re accreditation status. This PTH assay is currently not on our UKAS accreditation scope.

Tests not appearing on this scope are either under consideration or in the process of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff. 

Written by: Craig Webster Categories: Clinical Advice, Biochemistry